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Search Results for " transferrin receptor "

Targets Recommended: Others

10

抑制剂 & 化合物

14

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T40428L	TfR-T12 acetate TfR-T12 acetate (344618-30-0 Free base)	Others	Others
	TfR-T12 acetate 是一种与转铁蛋白受体 (TfR) 结合的肽，随后被内化到表达 TfR 的细胞中。
T34973	Tyrphostin 8 4-Hydroxybenzylidenemalononitrile	EGFR; GTPase	Angiogenesis; GPCR/G Protein; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	Tyrphostin 8(4-Hydroxybenzylidenemalononitrile) 是一种有效的 GTP 酶抑制剂，对 EGFR 激酶有抑制作用， IC50 值为 560 μM。Tyrphostin 8 可抑制蛋白丝氨酸/苏氨酸钙调磷酸酶 (IC50=21 μM)，增强 Caco-2 细胞中转铁蛋白受体介导的转吞作用，并增加口服胰岛素 - 转铁蛋白的降血糖作用。
T80622	Trontinemab
	Trontinemab为一种双特异性人源IgG1-κ抗体，靶向Aβ前体蛋白(APP)与转铁蛋白受体p90, CD71 (TFRC)。该抗体主要应用于阿兹海默症研究。
T78022	Transferrins
	Transferrin，一种血浆糖蛋白，作为转铁蛋白受体的特异性配体，能够结合并调控铁离子的运输。
T40428	TfR-T12 TfR-T12
	TfR-T12 is a transferrin receptor (TfR) binding peptide that can penetrate the blood-brain barrier (BBB), exhibiting a high binding affinity within the nanomolar (nM) range.
T15135L	Direct Black 38 free acid NSC8679,Ferristatin II	Others	Others
	Ferristatin II (Direct Black 38 free acid) is a polysulphonated dye and promotes the degradation of transferrin receptor-1 in vitro and in vivo.
T78374	TfR-T12 TFA
	TfR-T12 TFA为能穿透血脑屏障的转铁蛋白受体(TfR)结合肽，展现出纳摩尔级的结合活性。
T26639	Ap44mSe
	Ap44mSe is a potent and selective antitumor agent. Ap44mSe effectively depletes cellular Fe, resulting in transferrin receptor-1 up-regulation, ferritin down-regulation, and increased expression of the potent metastasis suppressor, N-myc downstream regula
T81573	Pabinafusp alfa JR-141
	Pabinafusp alfa (JR-141) 是由Iduronate 2-sulfatase和抗人转铁蛋白受体抗体结合而成的转铁蛋白受体靶向抗体。它具备穿透血脑屏障的能力，可防止粘多糖病II型(MPS II)小鼠中枢神经系统中硫酸肝素(HS)的积累。此外，Pabinafusp alfa能够促进小鼠的学习能力，并抑制中枢神经系统神经元的损伤。
T78014	HAIYPRH hydrochloride
	HAIYPRH hydrochloride为一种能特异性结合转铁蛋白受体（TfR）的靶向配体，可促进纳米载体穿越血脑屏障的介导转运。

化合物

TfR-T12 acetate

Cat.No: T40428L

Synonym: TfR-T12 acetate (344618-30-0 Free base)

Target: Others

Cat.No: T34973

Synonym: 4-Hydroxybenzylidenemalononitrile

Target: EGFR, GTPase

Cat.No: T80622

Cat.No: T78022

Cat.No: T40428

Synonym: TfR-T12

Direct Black 38 free acid

Cat.No: T15135L

Synonym: NSC8679,Ferristatin II

Target: Others

Cat.No: T78374

Cat.No: T26639

Pabinafusp alfa

Cat.No: T81573

Synonym: JR-141

HAIYPRH hydrochloride

Cat.No: T78014

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-03739	Transferrin Receptor/TFRC Protein, Cynomolgus, Rhesus, Recombinant (His) transferrin receptor	Cynomolgus,Rhesus	HEK293 Cells
	Transferrin Receptor/TFRC Protein, Cynomolgus, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 77.5 kDa and the accession number is XP_005545315.1&NP_001244232.1.
TMPY-05096	Transferrin Receptor/TFRC Protein, Human, Recombinant (hFc) CD71,T9,transferrin receptor,TFR1,p90,TRFR...	Human	HEK293 Cells
	Transferrin Receptor/TFRC Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 103.6 kDa and the accession number is CAA25527.1.
TMPY-01873	Transferrin Receptor/TFRC Protein, Human, Recombinant (His) TFR1,p90,CD71,TFR,transferrin receptor,T9,...	Human	HEK293 Cells
	Transferrin Receptor/TFRC Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 77.4 kDa and the accession number is AAA61153.1.
TMPY-02294	Transferrin Receptor/TFRC Protein, Mouse, Recombinant (His) 2610028K12Rik,p90,E430033M20Rik,AI426448,TFR,AU015758,Mtvr1,...	Mouse	HEK293 Cells
	Transferrin Receptor/TFRC Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 78.3 kDa and the accession number is Q62351.
TMPY-06661	Transferrin Receptor/TFRC Protein, Rat, Recombinant (His) transferrin receptor	Rat	HEK293 Cells
	Transferrin Receptor/TFRC Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 78.59 kDa and the accession number is Q99376.
TMPY-05617	Transferrin Receptor/TFRC Protein, Human, Recombinant (His), Biotinylated TRFR,p90,TR,TFR,CD71,TFR1,T9,transferrin recept...	Human	HEK293 Cells
	Transferrin Receptor/TFRC Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 77.4 kDa and the accession number is P02786.
TMPJ-00378	Transferrin Receptor/TFRC Protein, Human, Recombinant (aa 101-760, His) p90,TfR,T9,Trfr,Transferrin receptor prote...	Human	HEK293 Cells
	Transferrin receptor protein 1 (TFRC) belongs to the peptidase M28 family that is synthesized as a 172 amino acid (aa). TFRC regulated by cellular iron levels through binding of the iron regulatory proteins, IRP1 and IRP2, to iron-responsive elements in the 3'-UTR. It binds one transferrin or HFE molecule per subunit and binds the HLA class II histocompatibility antigen, DR1. It Interacts with SH3BP3 and STEAP3, facilitates TFRC endocytosis in erythroid precursor cells. Cellular uptake of iron o...
TMPH-03388	Transferrin Receptor/TFRC Protein, Rat, Recombinant (His & SUMO)	Rat	E. coli
	Transferrin Receptor/TFRC Protein, Rat, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 35.9 kDa and the accession number is Q99376.
TMPK-01261	Transferrin R/CD71 Protein, Cynomolgus, Recombinant (His) TFR,T9,CD71,TfR1,sTfR,TFRC,TR,p90	Cynomolgus	HEK293 Cells
	The transferrin receptor (CD71) is known as a receptor for IgA1 on mesangial cells. The transcript and protein expression of glomerular CD71 was determined by real-time polymerase chain reaction and immunohistochemistry. Human mesangial cells (HMCs) were treated with sera from IgAN patients and expression levels of CD71 and inflammatory cytokine markers were compared according to disease status. Transferrin R/CD71 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with...
TMPK-00374	Transferrin R/CD71 Protein, Human, Recombinant (His & Avi) p90,TFR,sTfR,T9,TFRC,TfR1,CD71,TR	Human	HEK293 Cells
	The transferrin receptor (CD71) is known as a receptor for IgA1 on mesangial cells. The transcript and protein expression of glomerular CD71 was determined by real-time polymerase chain reaction and immunohistochemistry. Human mesangial cells (HMCs) were treated with sera from IgAN patients and expression levels of CD71 and inflammatory cytokine markers were compared according to disease status. Transferrin R/CD71 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells wit...
TMPK-00375	Transferrin R/CD71 Protein, Human, Recombinant (His & Avi), Biotinylated TFRC,sTfR,T9,p90,CD71,TR,TFR,TfR1	Human	HEK293 Cells
	The transferrin receptor (CD71) is known as a receptor for IgA1 on mesangial cells. The transcript and protein expression of glomerular CD71 was determined by real-time polymerase chain reaction and immunohistochemistry. Human mesangial cells (HMCs) were treated with sera from IgAN patients and expression levels of CD71 and inflammatory cytokine markers were compared according to disease status. Transferrin R/CD71 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mamma...
TMPK-00376	Transferrin R/CD71 Protein, Human, Recombinant (hFc) sTfR,CD71,TfR1,TFR,p90,TFRC,TR,T9	Human	HEK293 Cells
	The transferrin receptor (CD71) is known as a receptor for IgA1 on mesangial cells. The transcript and protein expression of glomerular CD71 was determined by real-time polymerase chain reaction and immunohistochemistry. Human mesangial cells (HMCs) were treated with sera from IgAN patients and expression levels of CD71 and inflammatory cytokine markers were compared according to disease status. Transferrin R/CD71 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hF...
TMPH-03046	TBP1 Protein, MenB, Recombinant (His & Myc)	MenB	E. coli
	Neisseria acquires iron by extracting it from serum transferrin (TF) in its human host. Acts as a TF receptor and is required for TF utilization. Binds both apo- and holo-TF, via the TF C-terminus.
TMPH-02334	RAB12 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may play a role in protein transport from recycling endosomes to lysosomes regulating, for instance, the degrada...

重组蛋白

Transferrin Receptor/TFRC Protein, Cynomolgus, Rhesus, Recombinant (His)

Cat.No: TMPY-03739

Species: Cynomolgus,Rhesus

Expression System: HEK293 Cells

Transferrin Receptor/TFRC Protein, Human, Recombinant (hFc)

Cat.No: TMPY-05096

Species: Human

Expression System: HEK293 Cells

Transferrin Receptor/TFRC Protein, Human, Recombinant (His)

Cat.No: TMPY-01873

Species: Human

Expression System: HEK293 Cells

Transferrin Receptor/TFRC Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02294

Species: Mouse

Expression System: HEK293 Cells

Transferrin Receptor/TFRC Protein, Rat, Recombinant (His)

Cat.No: TMPY-06661

Species: Rat

Expression System: HEK293 Cells

Transferrin Receptor/TFRC Protein, Human, Recombinant (His), Biotinylated

Cat.No: TMPY-05617

Species: Human

Expression System: HEK293 Cells

Transferrin Receptor/TFRC Protein, Human, Recombinant (aa 101-760, His)

Cat.No: TMPJ-00378

Species: Human

Expression System: HEK293 Cells

Transferrin Receptor/TFRC Protein, Rat, Recombinant (His & SUMO)

Cat.No: TMPH-03388

Species: Rat

Expression System: E. coli

Transferrin R/CD71 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-01261

Species: Cynomolgus

Expression System: HEK293 Cells

Transferrin R/CD71 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00374

Species: Human

Expression System: HEK293 Cells

Transferrin R/CD71 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00375

Species: Human

Expression System: HEK293 Cells

Transferrin R/CD71 Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00376

Species: Human

Expression System: HEK293 Cells

TBP1 Protein, MenB, Recombinant (His & Myc)

Cat.No: TMPH-03046

Species: MenB

Expression System: E. coli

RAB12 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-02334

Species: Human

Expression System: E. coli

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